Table 2.
Major laboratory biomarkers* of patients with sepsis and septic shock, at baseline and one week after enrollment (n = 102).
| At Enrollment | One Week after Enrollment | |||||
|---|---|---|---|---|---|---|
| Laboratory Biomarkers | Sepsis (n = 60) |
Septic Shock (n = 42) |
p-Value | Sepsis (n = 60) |
Septic Shock (n = 42) |
p-Value |
| Hematologic indices | ||||||
| White Blood Cells a × 109/L | 12.5 ± 5.9 | 16.3 ± 10.7 | 0.02 | 8.5 ± 3.2 | 16.2 ± 11.1 | <0.001 |
| Platelets a × 109/L | 230.4 ± 117.6 | 195.8 ± 118.8 | 0.15 | 252.7 ± 120.3 | 174.6 ± 97.9 | 0.001 |
| Markers of organ dysfunction | ||||||
| Albumin a, g/L | 26 ± 5.6 | 22.6 ± 5.7 | 0.004 | 25.1 ± 4.8 | 22.5 ± 4.2 | 0.005 |
| Lactate b, mmol/L | 1.2 (1–5) | 2.4 (2.1–9) | <0.001 | 1 (1–2.7) | 1.9 (0.7–19) | <0.001 |
| Inflammatory biomarkers | ||||||
| CRP b, mg/L | 89 (7–218) | 174 (36–431) | <0.001 | 55 (8–282) | 101 (13–253) | 0.01 |
| Procalcitonin b, μg/L | 0.7 (0.09–47.7) | 4.8 (0.14–100) | 0.002 | 0.5 (0.06–15) | 1.4 (0.14–83) | 0.001 |
| IL-1β b, ng/L | 5.9 (5.9–207) | 8.8 (5.9–44.8) | 0.18 | 17 (5.9–499) | 8.8 (5.9–45) | 0.13 |
| IL-6 b, ng/L | 16.5 (6–385) | 74.4 (10–444) | 0.001 | 25 (4.6–419) | 20.5 (6–487) | 0.34 |
| IL-10 b, ng/L | 5 (5–300) | 6.9 (5–87) | 0.001 | 5 (5–300) | 5 (5–66) | 0.02 |
| suPAR b, μg/L | 10.5 (2.2–16.8) | 14.1 (4.4–16.8) | 0.04 | 11.3 (2.6–16.8) | 12.9 (5.2–16.8) | 0.68 |
| Chemerin a, μg/L | 299.7 ± 99.5 | 403.2 ± 89.9 | <0.001 | 261.6 ± 91.9 | 374.9 ± 95.3 | <0.001 |
*Values of normally distributed variables are reported as mean ± SD, and those of non-normally distributed variables are reported as median (range). Abbreviations: CRP, C-reactive protein; IL, interleukin; suPAR, soluble urokinase-type plasminogen activator receptor. a Mean ± SD, b Median, range.