Table 5.
Variables | At Enrollment | One Week after Enrollment | ||
---|---|---|---|---|
r | p | r | p | |
Clinical scoring | ||||
APACHE II | 0.48 | <0.001 | 0.36 | <0.001 |
SOFA | 0.49 | <0.001 | 0.35 | <0.001 |
Hematologic indices | ||||
Hemoglobin | 0.01 | 0.93 | −0.09 | 0.38 |
White Blood Cells | 0.24 | 0.01 | 0.21 | 0.03 |
Platelets | −0.06 | 0.55 | −0.38 | <0.001 |
Biomarkers of organ dysfunction | ||||
Albumin | −0.28 | <0.01 | −0.31 | 0.001 |
Lactate | 0.57 | <0.001 | 0.35 | <0.001 |
Creatinine | 0.31 | 0.001 | 0.16 | 0.11 |
Metabolic parameters | ||||
Total protein | −0.32 | 0.001 | −0.46 | <0.001 |
Glucose | 0.26 | 0.02 | - | - |
Insulin | 0.43 | 0.03 | - | - |
HOMA-IR | 0.47 | <0.001 | - | - |
BMI | 0.19 | 0.06 | - | - |
Coagulation biomarkers | ||||
Prothrombin time | 0.34 | <0.001 | 0.11 | 0.27 |
aPTT | 0.39 | <0.001 | 0.15 | 0.13 |
Fibrinogen | 0.04 | 0.67 | −0.11 | 0.28 |
Inflammatory biomarkers | ||||
CRP | 0.44 | <0.001 | −0.06 | 0.57 |
Procalcitonin | 0.226 | 0.02 | 0.16 | 0.11 |
IL-1β | 0.08 | 0.4 | −0.11 | 0.3 |
IL-6 | 0.14 | 0.16 | −0.10 | 0.32 |
IL-10 | 0.16 | 0.12 | −0.08 | 0.45 |
suPAR | 0.09 | 0.39 | 0.08 | 0.45 |
Abbreviations: APACHE II, acute physiology and chronic health evaluation score; aPTT, activated partial thromboplastin time; BMI, body mass index; CRP, C-reactive protein; HOMA-IR, homeostasis model assessment of insulin resistance; IL, interleukin; SOFA, sequential organ failure assessment score; suPAR, soluble urokinase-type plasminogen activator receptor.