TABLE 5.
Description of treatment failure with mutant strains
| Treatment and patient no. | Diseasea | Age (yr) | Sexb | Strain type before treatment | Strain type after treatment |
|---|---|---|---|---|---|
| Treatment without clarithromycinc | |||||
| 1 | DU | 47 | M | Wildd + A2144G | Wild + A2144G |
| 2 | GU | 38 | M | A2144G | A2144G |
| 3 | CG | 22 | F | Wild + A2144G | Wild + A2144G |
| 4 | DU | 47 | F | A2144G | A2144G |
| Treatment including clarithromycine | |||||
| 5 | CG | 54 | F | Wild + A2144G | A2144G |
| 6 | DU | 40 | M | Wild + A2144G | A2144G |
| 7 | GU | 38 | M | Wild + A2144G | A2144G |
| 8 | GU | 48 | M | Wild + A2144G | A2144G |
| 9 | GU | 60 | F | A2144G | A2144G |
| 10 | GU | 55 | F | A2144G | A2144G |
| 11 | CG | 55 | M | A2144G | A2144G |
| 12 | CG | 58 | M | Wild | A2144G |
a
DU, duodenal ulcer; GU, gastric ulcer; CG, chronic gastritis.
b
M, male; F, female.
c
Lansoprazole at 30 mg b.i.d. plus amoxicillin at 500 mg q.i.d. for 1 to 2 weeks.
d
Wild, wild type.
e
Lansoprazole at 30 mg b.i.d. plus amoxicillin at 500 mg q.i.d. and clarithromycin at 200 mg b.i.d. for 1 week.