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. 2022 Jan 29;10(2):317. doi: 10.3390/biomedicines10020317

Table 2.

Univariate and multivariate analyses of prognostic factors and overall survival of GBM patients.

Training Set Univariate Cox Regression Analysis Multivariate Cox Regression Analysis
HR 95% CI p-Value HR 95% CI p-Value
Risk (high/low) 2.719 2.218–3.334 6.352 × 10−22 2.471 2.006–3.044 1.839 × 10−17
Age (≥60/<60) 1.866 1.544–2.255 1.093 × 10−10 1.583 1.304–1.922 3.341 × 10−06
Gender (male/female) 0.852 0.703–1.033 0.103 0.957 0.789–1.162 0.657
Validation Set 1
Risk (high/low) 2.476 1.584–3.872 6.99 × 10−05 2.286 1.429–3.657 5.605 × 10−04
Age (≥60/<60) 1.796 1.061–3.041 0.029 1.365 0.788–2.364 0.267
Gender (male/female) 1.233 0.798–1.905 0.346 1.099 0.708–1.707 0.673
Validation Set 2
Risk (high/low) 2.293 1.573–3.343 1.592 × 10−05 2.17 1.481–3.179 7.026 × 10−05
Age (≥60/<60) 2.449 1.734–3.459 3.637 × 10−07 2.35 1.655–3.337 1.785 × 10−06
Gender (male/female) 0.902 0.637–1.277 0.56 0.823 0.579–1.168 0.275