Table 2.
Training Set | Univariate Cox Regression Analysis | Multivariate Cox Regression Analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p-Value | HR | 95% CI | p-Value | |
Risk (high/low) | 2.719 | 2.218–3.334 | 6.352 × 10−22 | 2.471 | 2.006–3.044 | 1.839 × 10−17 |
Age (≥60/<60) | 1.866 | 1.544–2.255 | 1.093 × 10−10 | 1.583 | 1.304–1.922 | 3.341 × 10−06 |
Gender (male/female) | 0.852 | 0.703–1.033 | 0.103 | 0.957 | 0.789–1.162 | 0.657 |
Validation Set 1 | ||||||
Risk (high/low) | 2.476 | 1.584–3.872 | 6.99 × 10−05 | 2.286 | 1.429–3.657 | 5.605 × 10−04 |
Age (≥60/<60) | 1.796 | 1.061–3.041 | 0.029 | 1.365 | 0.788–2.364 | 0.267 |
Gender (male/female) | 1.233 | 0.798–1.905 | 0.346 | 1.099 | 0.708–1.707 | 0.673 |
Validation Set 2 | ||||||
Risk (high/low) | 2.293 | 1.573–3.343 | 1.592 × 10−05 | 2.17 | 1.481–3.179 | 7.026 × 10−05 |
Age (≥60/<60) | 2.449 | 1.734–3.459 | 3.637 × 10−07 | 2.35 | 1.655–3.337 | 1.785 × 10−06 |
Gender (male/female) | 0.902 | 0.637–1.277 | 0.56 | 0.823 | 0.579–1.168 | 0.275 |