Table 1.

Data Exploration Module.

	App Function	Description
E1	Unsupervised Heatmap	Top variable gene selection Expression data is log2 transformed then z-normalized User-specified clustering method
E2	Scatter Plot	User selects two genes of interest Expression values compared via interactive scatter plot (log2 transformation is optional)
E3	Custom Heatmap	Visualize user-selected genes and samples Expression data is log2 transformed and z-normalized User-specified clustering method
E4	Box Plot	Gene expression in each group are shown Expression values are log2 transformed Comparing groups for statistical differences