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Interruption of T cell differentiation. Small molecules inhibiting key metabolic and developmental pathways might cause an interruption of the T cell differentiation process from naïve-like T (TN) cells and stem cell memory-like T (TSCM) cells towards T central memory-like (TCM) cells, T effector memory-like (TEM) cells, and terminally differentiated T effector-like (TE) cells.
