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. 2022 Jan 29;12(2):81. doi: 10.3390/bios12020081

Table 3.

A brief overview of the advantages and limitations of optical and electrochemical aptasensors for virus detection.

Transducer Type Advantages Limitations References
Optical Real-time detection;
reliable, high sensitivity
Sensitive to the surrounding environment;
surface modification is one of the main challenges;
bulky optical devices required
[114,129]
Electrochemical Simplicity, miniaturization, low cost
real-time detection; the possibility of continuous analysis on different analytes
Need redox elements to enhance the current production; time consuming; sensitive to the surrounding environment [83,87]