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. 2022 Jan 28;11(2):213. doi: 10.3390/biology11020213

Figure 5.

Figure 5

Characterization of let-7 clusters in P. olivaceus genome. (a) Consensus sequence of the 20 P. olivaceus let-7 members with seed sequence “GAGGUAG”; (b) Putative evolutionary trajectory of the let-7/miR-125b clusters across vertebrates (modified and referenced from [48]). Red triangles represent miR-100, yellow triangles represent miR-125b, while let-7 sequences are shown as blue triangles. 1R/2R indicate two rounds of whole genome duplications, while TS-WGD represents the additional teleost-specific genome duplication. The duplicate clusters in teleost are highlighted as two boxes; (c) Detailed annotation of P. olivaceus let-7 clusters with six putative lncRNA precursors; (d) Synteny for let-7 cluster D. The pentagon’s direction shows the gene direction compared with the reference gene.