Table 1.
(a) | Subclass and Chemical Structure | Role in Diseases | |||
Carotenoids (tetraterpenoids) | Carotenes | α-Carotene [70,71] |
Cardiovascular [72] | ||
β-Carotene [70] |
Cardiovascular [72] Cancer [73] Neurodegenerative [74,75] |
||||
Lycopene [70,76] |
Cancer [77,78,79] Diabetes [80] Cardiovascular [72,81,82] Neurodegenerative [74,75] Skin [83,84,85,86,87] |
||||
Neurosporene [88,89,90] |
Skin [91] | ||||
Phytoene [89,92] |
Skin [93] | ||||
Phytofluene [89,94] |
Skin [93] | ||||
Glycoalkaloids | Saponins | Tomatine [95,96] |
Cancer [97] Cardiovascular [95] Malaria [98] |
||
Esculeoside A [99,100] |
Diabetes [100] | ||||
Lycoperoside H [62,101] |
Skin [62] Inflammation [101] |
||||
(b) | |||||
Polyphenols | Flavonoids | Kaempferol [102,103] |
Quercetin [102,104] |
Naringenin [102,105] |
Diabetes [106,107] Skin [108] Neurodegenerative [109] |
Phenolic acids | Caffeic acid [102,110] |
p-Coumaric acid [102,111] |
Ferulic acid [102,112] |
Cancer [113,114,115] | |
Stillbenoids | Resveratrol [116,117] |
Cancer [118,119] Diabetes [118] Cardiovascular [118] Neurodegenerative [120] Skin [121,122] |
|||
Anthocyanins | Delphinidin [123,124] |
Petunidin [123,125,126] |
Cancer [127] Cardiovascular [127,128] Neurodegenerative [128] Skin [127] IBD [127,129,130] |
||
Vitamins | B | Folate (vitamin B9) [70,131] |
Infertility [132] | ||
C | Ascorbic acid [70,133] |
Cancer [134] Diabetes [135] Skin [136,137] |
|||
E | α-Tocopherol [70,138] |
Cancer [134] Diabetes [135] Cardiovascular [139] Infertility [140] |
|||
K | Phylloquinone (vitamin K1) [70] |
Atherosclerosis [141] |