Table 2.
Sensitivity, specificity, and positive/negative predictive values of tumor markers for the detection of malignant non-germinomatous germ cell tumor components among cases with tumor resection.
| Tumor Markers | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| HCG ≧ 100 IU/L | 61.5% | 82.1% | 53.3% | 86.5% |
| 8/13 | 32/39 | 8/15 | 32/37 | |
| AFP ≧ 10 ng/mL | 83.3% | 78.0% | 57.7% | 92.9% |
| 15/18 | 39/50 | 15/26 | 39/42 | |
| Either or both | 94.7% | 52.8% | 51.4% | 95.0% |
| 18/19 | 19/36 | 18/35 | 19/20 |
Abbreviations: HCG; human chorionic gonadotropin, AFP; alpha fetoprotein, PPV; positive predictive value, NPV; negative predictive value.