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. 2022 Feb 16;14(4):1005. doi: 10.3390/cancers14041005

Table 1.

Published reports (more than 13 patients) on the efficacies of first-line antibiotics treatment in HP-negative gastric MALT lymphomas.

Author Country N Stage CR Rate
N (%)
Median
Time to CR: m (Range)
HP Test HPE t(11;18) Ref.
Nakamura
T, et al.
Japan 17 IE: 16
IIE1: 1
2 (11.8) ND H, RUT, S A + C + P with/without
M
CR: 1/2(+)
Non-CR:
7/15(+)
[34]
Nakamura S, et al. Japan 44 ND 6 (13.6) ND H, C, RUT, UBT, S A + C + P
C + M + P
A + M + P
NA [35]
Stathis et al. Switzerland 14 IE: 9
IIE1: 5
5 (35.7) ND H, UBT, S A + C + P, C + M + P, or A + M + P NA [36]
Asano et al. Japan 17 IE: 15
IIE: 2
5 (29.4) ND H, RUT, UBT, S A + C + P (16 pts)
Or
A + M + P (1 pt)
CR: 1/2(+),
Non-CR:
6/9 (+)
[37]
Raderer et al. Austria 13 IE: 8
IIE1: 5
5 (38.5) 3–36 H, UBT, S C + M + P or C + A + P
(7 or 14 D)
CR: 0/5(+),
Non-CR: 3/8(+)
[30]
Gong et al. Korea 28 IE: 24
IIE: 1
IV: 3
16 (57.1) 11.5
(10.0–22.3)
H, RUT, UBT, S A + C + P
7D or 14 D
NA [38]
Kuo et al. Taiwan 25 IE: 22
IIE1: 3
8 (32.0) 6.1(1–24) H, RUT,
UBT, S, C
A + C + P
14 D
CR: 0/7(+)
Non-CR: 6/13 (+)
[16]
Strati et al. USA 26 IE: 26 6 (23.1) 2 (1–6) H, S A + C + P
or M + C + P; 14 D
Non-CR: 0/3 [39]

Abbreviation: N, number; CR, complete remission; m, month; HP, Helicobacter pylori; HPE, HP eradication; t(11;18), t(11;18)(q21;q21); Ref, reference; ND, non-described; NA, non-analysis; pt, patient. HP examination test: H, histology; RUT, rapid urease test; UBT, urea breath test; S, serological test; C, culture; HPE regimen: A, amoxicillin; C, clarithromycin; M, metronidazole; P, proton-pump inhibitor, including lansoprazole, pantoprazole or esomeprazole for 7 to 14 days (D).