Figure 1.

Higher intratumoral levels of ADCK2 correlate with better survival of melanoma patients. (A): The relative expression of ADCK2 in nine melanoma cell lines is as high or lower compared to normal human melanocytes and is not affected by the mutational status of the melanoma cells. Statistical analysis was performed with paired t-test. (n = 4). (B): Data from two distinct datasets from the cBioPortal database show that a higher intratumoral level of ADCK2 goes along with better disease-specific survival of melanoma patients. Statistical analysis of the survival data was performed with a log-rank test. Median survival: left graph high = 32.27, low = 5933 months; right graph high = undefined, low = 14.4 months. * p ≤ 0.05; *** p ≤ 0.001; ns = not significant.