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. 2022 Feb 20;14(4):1071. doi: 10.3390/cancers14041071

Figure 6.

Figure 6

Knockdown of MYL6 negates the effect of ADCK2 OE on melanoma cells. (A): The expression of ADCK2 was not altered upon MYL6 knockdown (n = 4). (B): No significant difference in the expression of MYL6 could be detected between EV and OE ADCK2 cells (n = 4). (C): MYL6 expression was significantly reduced in SkMel28 OE ADCK2 cells upon treatment with siMYL6 compared to siControl (n = 4). (D): Lower levels of MYL6 led to a decreased cell viability of SkMel28 OE ADCK2 cells compared to control cells (n = 6). (E): The migration capacity of SkMel28 OE cells was increased by siMYL6 treatment compared to siControl treatment (n = 4). All statistical analyses were conducted with paired t-tests. * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; ns = not significant.