Table 5.
Parameter | Group | F Value | p Value | |||
---|---|---|---|---|---|---|
Vehicle (n = 6) |
Dasatinib Control (n = 6) |
Obese (n = 6) |
Obese + Dasatinib (n = 6) |
|||
Glomerulosclerosis | 0(0–1) A |
0(0–1) A |
4(2–4) B |
2(1–2) C |
50.523 | <0.0005 |
Tubular dilatation | 0(0–1) A |
0(0–1) A |
3.5(2–4) B |
1.5(1–2) C |
51.044 | <0.0005 |
Cast formation | 0(0–0.75) A |
0(0–1) A |
4(2.25–4) B |
1.5(1–2) C |
54.227 | <0.0005 |
Tubular vacuolation | 0(0–1) A |
0(0–1) A |
4(2–4) B |
1.5(1–2) C |
46.877 | <0.0005 |
Inflammatory cellular infiltrate | 0(0–1) A |
0(0–1) A |
3(2–3.75) B |
1(1–2) C |
48.078 | <0.0005 |
Tubulointerstitial fibrosis | 0(0–1) A |
0(0–1) A |
3(2–4) B |
1.5(1–2) C |
52.222 | <0.0005 |
Score | 3 (2–3.75) A |
3(2–4) A |
19.5(17–21) B |
9(7.25–10) C |
67.305 | <0.0005 |
Results are tabulated as median and interquartile range. Different letters = significant difference.