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. 2022 Feb 14;11(4):667. doi: 10.3390/cells11040667

Figure 6.

Figure 6

Administration of imipramine reduced the number of apoptotic cells after hypoglycemia: (A) cleaved caspase-3 (red) and NeuN (green) in the hippocampus CA1 region. After hypoglycemia, the administration of imipramine for 1 week decreased the number of apoptotic cells and increased the number of live neurons compared to the hypoglycemia-vehicle group. Scale bar = 100 µm. (B) The bar graph indicates the quantification of the apoptotic cell number. Data are the mean ± SEM; n = 3 from each group. Individual data points (● = Sham-Veh, ■ = Sham-IMP, ▲ = HG-Veh, ▼ = HG-IMP). * Significantly different from the vehicle-treated group at p < 0.05.