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. 2022 Feb 16;14(4):987. doi: 10.3390/cancers14040987

Table 3.

Sensitivity, specificity, and area under the receiver operating characteristic curve of the convolutional neural network.

Sequence Interpreter Sensitivity 95% CI Specificity 95% CI Accuracy 95% CI AUC 95% CI p-Value for AUC (Versus CNN)
T2WI CNN 0.77 0.68–0.84 0.85 0.76–0.91 0.81 0.72–0.87 0.83 0.74–0.91 -
Reader 1 0.63 0.54–0.68 0.90 0.82–0.96 0.77 0.69–0.82 0.89 0.82–0.95 0.127
Reader 2 0.85 0.77–0.91 0.87 0.79- 0.92 0.86 0.78–0.92 0.91 0.85–0.97 0.048 *
Reader 3 0.75 0.66–0.82 0.85 0.76–0.91 0.80 0.71–0.86 0.88 0.81–0.94 0.305
DWI CNN 0.85 0.77–0.91 0.85 0.77–0.90 0.85 0.77–0.91 0.88 0.81–0.95 -
Reader 1 0.71 0.61–0.79 0.77 0.68–0.84 0.74 0.65–0.82 0.81 0.72–0.89 0.151
Reader 2 0.65 0.55–0.73 0.71 0.62–0.79 0.68 0.58–0.76 0.74 0.64–0.84 0.004 *
Reader 3 0.79 0.70–0.87 0.75 0.66–0.82 0.77 0.68–0.84 0.82 0.73–0.90 0.135
ADC map CNN 0.85 0.76–0.92 0.77 0.69–0.83 0.81 0.72–0.87 0.89 0.83–0.96 -
Reader 1 0.81 0.72–0.88 0.75 0.66–0.82 0.78 0.69–0.85 0.84 0.77–0.92 0.263
Reader 2 0.92 0.83–0.97 0.36 0.29–0.41 0.63 0.55–0.68 0.79 0.70–0.88 0.023 *
Reader 3 0.77 0.68–0.84 0.79 0.70–0.86 0.78 0.69–0.85 0.85 0.78–0.93 0.356
CE-T1WI CNN 0.81 0.73–0.86 0.92 0.85–0.97 0.87 0.79–0.92 0.86 0.78–0.94 -
Reader 1 0.73 0.65–0.78 0.92 0.85–0.97 0.83 0.75- 0.88 0.87 0.79–0.94 0.903
Reader 2 0.75 0.66–0.82 0.83 0.74–0.89 0.79 0.70–0.86 0.85 0.77–0.92 0.730
Reader 3 0.75 0.65–0.83 0.71 0.62–0.79 0.73 0.64–0.81 0.82 0.73–0.90 0.416

ADC: apparent diffusion coefficient; AUC: area under the receiver operating characteristic curve; CE-T1WI: contrast-enhanced fat-saturated T1-weighted imaging; CI: confidence interval; CNN: convolutional neural network; DWI: diffusion-weighted imaging; T2WI: T2-weighted imaging. * p < 0.05.