Table 1.
PBRM1 expression in cancer cells with clinicopathological factors in 425 cases with nonmetastatic ccRCC.
| Variables | PBRM1 Retention | PBRM1 Loss |
|---|---|---|
| Gender, n (%) | ||
| Female | 81 (71.7) | 32 (28.3) |
| Male | 196 (62.8) | 116 (37.2) |
| TNM stage, n (%) | ||
| I | 242 (78.1) | 68 (21.9) |
| II | 3 (23.1) | 10 (76.9) |
| III | 32 (32.0) | 68 (68.0) |
| IV | 0 (0.0) | 2 (100.0) |
| WHO/ISUP grade, n (%) | ||
| 1 | 58 (96.7) | 2 (3.3) |
| 2 | 155 (68.0) | 73 (32.0) |
| 3 | 58 (52.7) | 52 (47.3) |
| 4 | 6 (22.2) | 21 (77.8) |
| Necrosis, n (%) | ||
| Absent | 256 (71.1) | 104 (28.9) |
| Present | 21 (32.3) | 44 (67.7) |
| Histological phenotype, n (%) | ||
| Clear | 201 (77.3) | 59 (22.7) |
| Mixed | 71 (49.0) | 74 (51.0) |
| Eosinophilic | 5 (25.0) | 15 (75.0) |
| Vascularity-based architectural classification, n (%) | ||
| Category 1 | 218 (79.0) | 58 (21.0) |
| Category 2 | 55 (45.1) | 67 (54.9) |
| Category 3 | 4 (14.8) | 23 (85.2) |
| Recurrence, n (%) | 11 (19.3) | 46 (80.7) |
| Cancer-specific mortality, n (%) | 2 (13.3) | 13 (86.7) |