Table 2.

RADD lesion-specific cocktails. For detecting specific lesion classes, the lesion processing mix is modified with only the specific DNA repair enzymes of interest for that lesion class.

Cocktails	Lesion Processing Mix	Lesions
oxRADD	FPG + EndoIV + EndoVIII	Removes various types of oxidized purines, urea, 5, 6-dihydroxythymine, thymine glycol, 5-hydroxy-5-methylhydanton, 6-hydroxy-5,6-dihydrothymine and methyltartronylurea, abasic sites, and strand breaks.
T4PDG	T4 PDG + EndoIV	Removes cyclobutane pyrimidine dimers and 6-4 photoproducts along with abasic sites.
UDG	UDG + EndoIV	Removes uracil lesions and abasic sites.
Full RADD	AAG + FPG + T4 PDG + UDG + EndoIV	All of the above lesions plus the removal of various alkylated and oxidative DNA damaged sites, including 3-methyladenine, 7-methylguanine, 1, N6-ethenoadenine, and hypoxanthine.