Table 1.
Patient characteristics among the groups of WHO grade 1 and 2 meningioma (n = 541). Statistical analysis was performed using independent t-test and Pearson’s chi-squared test (two-sided).
| Variable | Cranial (n = 418) |
Spinal (n = 123) |
p-Value |
|---|---|---|---|
| Sex | 0.09 | ||
| Female | 290 (69.4%) | 95 (77.2%) | |
| Male | 128 (30.6%) | 28 (22.8%) | |
| Age | 0.001 | ||
| Mean +/− SD | 60.7 +/− 13.6 | 65.6 +/− 12.4 | |
| Baseline KPS | 0.001 | ||
| Mean +/− SD | 89.8 +/− 11.5 | 82.1 +/− 11.0 | |
| BMI | 0.12 | ||
| Mean +/− SD | 27.3 +/− 5.9 | 28.3 +/− 5.1 | |
| Serum CRP | 0.04 | ||
| Mean +/− SD | 3.5 +/− 8.0 | 5.5 +/−9.8 | |
| Plasma fibrinogen | 0.003 | ||
| Mean +/− SD | 3.0 +/− 0.8 | 3.4 +/− 0.8 | |
| WHO grade | 0.005 | ||
| 1 | 344 (82.3%) | 114 (92.7%) | |
| 2 | 74 (17.7%) | 9 (7.3%) | |
| Mitotic count | 0.002 | ||
| Mean +/− SD | 1.9 +/− 2.8 | 1.1 +/− 1.2 | |
| MIB-1 index | 0.007 | ||
| Mean +/− SD | 5.4 +/− 3.0 | 4.3 +/− 2.4 | |
| CD68+ staining (n = 376) | 0.001 | ||
| Focal | 80 (27.8%) | 44 (50.0%) | |
| Diffuse | 208 (72.2%) | 44 (50.0%) | |
| CD68− staining (n = 165) | 130 (31.1%) | 35 (28.5%) | 0.27 |