Table 1.
Reference | Number of Patients | Statistical Significance |
---|---|---|
Ryschich et al. 2005 [44] | 46 | NS |
Tewari et al. 2013 [45] | 81 | Significantly associated with improved OS |
Chen et al. 2014 [46] | 63 | Significantly associated with improved OS |
Helm et al. 2014 [47] | 42 | NS |
Zhou et al. 2015 [51] | 158 | Significantly associated with improved OS (RR = 0.611) |
Hwang et al. 2016 [52] | 30 | NS |
Lundgren et al. 2016 [53] | 175 | Significantly associated with improved OS (HR = 0.42) |
Lohneis et al. 2017 [56] | 165 | NS |
Ino et al. 2019 [58] | 241 | Significantly associated with improved OS and DFS |
Miksch et al. 2019 [59] | 57 | Significantly associated with improved OS and DFS |
DFS: disease-free survival; HR: hazard ratio; NS: not significant; OS: overall survival; RR: relative risk.