Table 1.
The function of mitophagy in viral infection.
| Virus | Induction/Inhibition of Mitophagy | Target | Mitophagy in Virus Infections |
Viral Proteins Related to Mitophagy | References |
|---|---|---|---|---|---|
| HIV | Inhibition | - | Inhibition | gp120 and Tat | [20] |
| HBV | Induction | DNM1L | Promotion | - | [23] |
| HCV | Induction | DNM1L; Parkin |
Promotion | NS5A | [22,26] |
| CVB | Induction | DNM1L; PINK1/Parkin; NDP52; P62 |
Promotion/inhibition | VP1 | [27,49,55] |
| VEEV | Induction | DNM1L; PINK1/Parkin |
Promotion | - | [32] |
| DENV | Induction | DRP1 | Promotion | NS4B | [35] |
| IAV | Induction of incomplete autophagy | LC3; NDP52; MAVS ATG5 |
Promotion | M2; PB1-F2 |
[33] |
| Mev | Induction | NDP52; | - | Mev-C; Mev-V |
[52,53] |
| HPIV | Induction | TUFM; LC3 |
Promotion | M | [33,34,44] |
| MV-Edm (measles virus, Edmunston strain) | Induction | p62 | Promotion | - | [43] |
| BKPyV | Induction | p62; Agnoprotein |
Promotion | - | [45] |
| CSFV | Induction | DNM1L; PINK1/Parkin | Promotion | - | [24,25,42] |
| PRV | Inhibition in Vero cells/Induction in N2a cells | - | Promotion | - | [30,31] |
| PRRSV | Induction of incomplete autophagy | DNM1L; ROS |
Promotion | - | [28] |
| TEGV | Induction | PARK7/DJ-1 | Promotion | - | [29] |
| SARS-CoV | Induction of mitochondrial elongation | - | - | ORF-9b | [36] |