TABLE 5.
Logistic Regression Analysis of Factors Associated With Loss to Follow‐up
| Variable | Attended SVR12 (n = 9,174) | Did Not Attend SVR12 (n = 1,669) | Unadjusted | Adjusted | ||
|---|---|---|---|---|---|---|
| OR | P | OR † | P | |||
| (95% CI) | (95% CI) | |||||
| Sex | ||||||
| Female (ref) | 2,842 (85) | 499 (15) | — | — | ||
| Male | 6,318 (84) | 1,166 (16) | 1.01 (0.89‐1.13) | 0.09 | 1.06 (0.93‐1.20) | 0.38 |
| Transgender | 14 (78) | 4 (22) | 1.42 (0.45‐4.56) | 0.55 | 1.28 (0.40‐4.16) | 0.68 |
| Age, median (IQR) | ||||||
| Age in years | 52 (43‐58) | 45 (38‐54) | 0.96 (0.96‐0.97) | <0.01 | 0.97 (0.97‐0.98) | <0.01 |
| Age | ||||||
| ≥60 (ref) | 1651 (92) | 148 (8) | — | |||
| 50‐59 | 3433 (89) | 445 (11) | 1.42 (1.17‐1.74) | <0.01 | ||
| 40‐49 | 2,325 (81) | 531 (19) | 2.43 (1.99‐2.97) | <0.01 | ||
| 30‐39 | 1,381 (77) | 419 (23) | 3.25 (2.64‐4.02) | <0.01 | ||
| 18‐29 | 384 (75) | 126 (25) | 3.45 (2.60‐4.56) | <0.01 | ||
| Indigenous identification | ||||||
| No (ref) | 6,922 (86) | 1,174 (15) | — | — | ||
| Yes | 697 (76) | 218 (24) | 1.70 (1.42‐2.03) | <0.01 | 1.21 (1.00‐1.46) | 0.05 |
| Unknown | 1555 (85) | 277 (15) | 1.19 (0.97‐1.41) | 0.09 | 1.04 (0.86‐1.26) | 0.69 |
| Cirrhosis* | ||||||
| No (ref) | 7,076 (84) | 1,362 (16) | — | — | ||
| Yes | 2,067 (88) | 286 (12) | 0.81 (0.70‐0.94) | <0.01 | 1.04 (0.89‐1.22) | 0.60 |
| Unknown | 31 (60) | 21 (40) | 2.48 (1.37‐4.47) | <0.01 | 1.38 (0.75‐2.55) | 0.31 |
| IDU/OST | ||||||
| Neither (ref) | 5,285 (89) | 689 (11) | — | — | ||
| IDU only | 720 (73) | 264 (27) | 2.52 (2.10‐3.02) | <0.01 | 1.76 (1.45‐2.14) | <0.01 |
| IDU + OAT | 602 (77) | 184 (23) | 2.02 (1.63‐2.51) | <0.01 | 1.44 (1.15‐1.80) | <0.01 |
| OAT only | 958 (83) | 193 (17) | 1.52 (1.26‐1.84) | <0.01 | 1.39 (1.14‐1.70) | <0.01 |
| Unknown | 1,509 (82) | 339 (18) | 1.98 (1.68‐2.33) | <0.01 | 1.89 (1.59‐2.25) | <0.01 |
| HIV status | ||||||
| Negative (ref) | 8,379 (85) | 1,523 (15) | — | — | ||
| Positive | 370 (93) | 28 (7) | 0.38 (0.25‐0.59) | <0.01 | 0.39 (0.25‐0.61) | <0.01 |
| Unknown | 425 (78) | 118 (22) | 1.50 (1.17‐1.89) | <0.01 | 1.23 (0.96‐1.57) | 0.10 |
| Previous HCV treatment | ||||||
| No (ref) | 7,809 (84) | 1,520 (16) | — | — | ||
| Yes – interferon‐free | 129 (83) | 27 (17) | 0.95 (0.62‐1.47) | 0.82 | 0.66 (0.42‐1.05) | 0.08 |
| Yes – interferon‐containing | 1,162 (93) | 87 (7) | 0.42 (0.33‐0.52) | <0.01 | 0.58 (0.46‐0.73) | <0.01 |
| Unknown | 74 (68) | 35 (32) | 1.54 (1.00‐2.37) | 0.05 | 1.18 (0.75‐1.86) | 0.48 |
| Service type | ||||||
| Specialist liver clinic (ref) | 5,129 (89) | 633 (11) | — | — | ||
| GP/SHS/CHC | 2,620 (80) | 672 (20) | 1.97 (1.35‐2.88) | <0.01 | 1.39 (0.95‐2.03) | 0.09 |
| Drug and alcohol service | 546 (80) | 139 (20) | 1.84 (1.14‐2.96) | 0.01 | 1.17 (0.72‐1.90) | 0.52 |
| Prison | 549 (81) | 130 (19) | 1.62 (0.92‐2.87) | 0.10 | 0.59 (0.34‐1.05) | 0.08 |
| Other | 322 (78) | 91 (22) | 2.44 (1.43‐4.14) | <0.01 | 1.28 (0.76‐2.14) | 0.36 |
| Unknown | 8 (67) | 4 (33) | 3.82 (0.76‐19.17) | 0.10 | 3.02 (0.58‐15.64) | 0.19 |
| Location of health service provision | ||||||
| Major city (ref) | 5,934 (85) | 1,011 (15) | — | — | ||
| Regional or remote | 3,240 (83) | 658 (17) | 1.31 (0.93‐1.83) | 0.12 | 1.37 (1.00‐1.88) | 0.05 |
| Year of treatment initiation | ||||||
| 2016 (ref) | 4,867 (91) | 474 (9) | — | — | ||
| 2017 | 2,575 (83) | 536 (17) | 2.32 (2.02‐2.67) | <0.01 | 2.16 (1.87‐2.49) | <0.01 |
| 2018 | 1,348 (74) | 483 (26) | 3.94 (3.37‐4.60) | <0.01 | 3.63 (3.09‐4.27) | <0.01 |
| 2019 | 384 (69) | 176 (31) | 4.74 (3.80‐5.90) | <0.01 | 4.49 (3.57‐5.64) | <0.01 |
Data are presented as n (%) unless otherwise specified.
*
Determined by any method.
†
n=10,843.
Abbreviations: CHC, community health center; GP, general practice; SHS, sexual health service.