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. 2022 Feb 17;11(4):704. doi: 10.3390/cells11040704

Figure 6.

Figure 6

Control of the G2/M transition by cdc2/cyclin B. Cyclin B is progressively synthesised during G2 and binds to cdc2 to activate its kinase activity, thereby triggering entry into mitosis. Cyclin B is then rapidly degraded, leading to inactivation of cdc2 kinase, which triggers exit from mitosis.