Table 1.
Top 10 miRNAs implicated in CVDs.
| Mature_Mirna | Targeted Genes | SNPs | Drugs | Disease_Drug | |
|---|---|---|---|---|---|
| 1 | miR-155-5p | 241 | 5 | 15 | Cardiac hypertrophy; hypertension |
| 2 | miR-21-5p | 153 | 4 | 11 | Myocardial infarction; heart failure; vascular disease; cardiac hypertrophy; cardiomyopathy, dilated; stroke |
| 3 | miR-145-5p | 151 | 3 | 9 | Vascular disease; supravalvar aortic stenosis |
| 4 | miR-34a-5p | 148 | 4 | 31 | Stroke |
| 5 | miR-125b-5p | 126 | 5 | 4 | Cardiac hypertrophy; heart failure; vascular disease; cardiomyopathy, dilated; supravalvar aortic stenosis; cardiovascular; cardiomyopathy, idiopathic dilated; stroke |
| 6 | miR-29a-3p | 123 | 7 | 28 | Cardiac hypertrophy; cardiomyopathy, dilated; stroke |
| 7 | miR-24-3p | 110 | 4 | 1 | Cardiac hypertrophy; heart failure; cardiovascular; cardiomyopathy, dilated; supravalvar aortic stenosis; stroke |
| 8 | miR-29b-3p | 109 | 6 | 15 | Cardiac hypertrophy; myocardial infarction; cardiomyopathy, dilated; stroke |
| 9 | miR-200c-3p | 98 | 3 | 5 | Cardiomyopathy, dilated |
| 10 | miR-17-5p | 95 | 3 | 8 | Cardiomyopathy, dilated; stroke |