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. 2022 Feb 20;14(4):1067. doi: 10.3390/cancers14041067

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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CUDC-907 inhibits NB colony formation and growth. Colony formation assays in response to CUDC-907 in four NB cell lines. (A) Representative images of colony formation assays in MYCN-amplified cell lines NGP and LAN-5, and MYCN non-amplified cell lines SH-SY-5Y and SK-N-AS in response to CUDC-907 treatment. Cells were treated with CUDC-907 for 48 h. (B) Survival index graphs showing the quantitation of the relative inhibition of colony formation in the respective cell lines in response to CUDC-907 treatment. Colony numbers are normalized to control. *** p < 0.001, **** p < 0.0001.