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. 2022 Feb 11;16(2):e0009971. doi: 10.1371/journal.pntd.0009971

Table 2. Pooled prevalence of intestinal protozoan infections in different subgroups.

Subgroups Prevalence [95% CIs] (%) Number of studies analysed Total number of subjects Heterogeneity Publication Bias, Egger’s test (p-value)
I 2 p-value
Children enrolment time
Year 2005–2010 19.4 [12.5–26.4] 9 3,168 99% <0.0001 NA
Year 2011–2015 23.5 [9.3–37.7] 10 4,107 99% <0.0001 0.45
Year 2016–2020 25.2 [6.9–43.4] 9 3,314 100% <0.0001 NA
Different regions of Africa
Northern Africa 40.2 [22.7–57.6] 4 844 97% <0.0001 NA
Eastern Africa 21.9 [17.0–26.8] 23 15,906 99% <0.0001 0.02
Central Africa 21.5 [10.1–32.8] 4 1,412 97% <0.0001 NA
Western Africa 32.3 [15.1–49.5] 11 5,873 100% <0.0001 0.20
Southern Africa 18.6 [14.5–22.8] 4 5,933 92% <0.0001 NA
Countries
Ethiopia 15.3 [11.7–19.0] 17 13,975 99% <0.0001 <0.0001
Nigeria 24.3 [10.7–37.8] 6 2,599 99% <0.0001 NA
South Africa 15.6 [13.3–17.9] 3 5,666 77% 0.01 NA
Angola 13.7 [1.2–26.2] 2 558 95% <0.0001 NA
Ghana 6.3 [0.0–15.2] 2 850 96% <0.0001 NA
Kenya 36. 5 [27.9–45.1] 2 276 52% 0.14 NA
Egypt 25.5 [13.2–37.7] 2 564 91% <0.0001 NA
Burkina Faso 84.7 [81.1–88.3] 1 385 NA NA NA
DR Congo 30.1 [26.4–33.7] 1 602 NA NA NA
Eritrea 38.2 [33.7–42.7] 1 450 NA NA NA
Mauritania 31.0 [28.5–33.5] 1 1308 NA NA NA
Morocco 57.7 [49.0–66.5] 1 123 NA NA NA
Rwanda 35.7 [31.9–39.5] 1 622 NA NA NA
Sao Tome Principe 28.6 [23.0–34.1] 1 252 NA NA NA
Senegal 80.4 [77.6–83.3] 1 731 NA NA NA
Sudan 52.9 [45.1–60.7] 1 157 NA NA NA
Swaziland 32.2 [26.6–37.8] 1 267 NA NA NA
Uganda 87.0 [82.9–91.1] 1 254 NA NA NA
Zambia 10.0 [6.8–13.3] 1 329 NA NA NA
Different diagnostic methods
Microscopy 22.7 [18.8–26.6] 40 26,489 99% <0.0001 <0.0001
PCR or qPCR 61.4 [35.3–87.4] 4 1,703 99% <0.0001 NA
Rapid diagnostic kit 14.5 [12.6–16.3] 4 1,776 21% 0.16 NA
Different species
Giardia spp. 12.0 [9.8–14.3] 38 26,565 99% <0.0001 0.0003
E. histolytica/ dispar 13.3 [10.7–15.9] 33 13,235 99% <0.0001 <0.0001
Entamoeba coli 17.1 [10.9–23.2] 9 3,788 97% <0.0001 NA
Cryptosporidium spp. 2.5 [1.8–3.2] 3 2,076 3% 0.35 NA

CIs: Confidence intervals; NA: Not applicable.