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. 2022 Feb 10;8:811670. doi: 10.3389/fcvm.2021.811670

Table 4.

HRs for 7-year CVD and all-cause death associated with WC/HHcy groups.

NWC/HHcy (–) NWC/HHcy (+) HWC/HHcy (–) HWC/HHcy (+)
(n = 897, 24.4%) (n = 599, 16.3%) (n = 1,305, 35.5%) (n = 874, 23.8%)
CVD death
Case 19 26 35 55
Mortality 2.1% 4.3% 2.7% 6.3%
Model 1 1.00 2.12 (1.17, 3.83)* 1.26 (0.72, 2.19) 3.16 (1.87, 5.32)*
Model 2 1.00 1.34 (0.73,2.46) 1.13 (0.64, 2.00) 1.79 (1.05, 3.07)*
Model 3 1.00 1.36 (0.74, 22.51) 1.06 (0.60, 1.89) 1.75 (1.02, 3.03)*
All-cause death
Case 80 100 110 164
Mortality 8.9% 16.7% 8.4% 18.7%
Model 1 1.00 1.74 (1.24, 2.50)* 0.94 (0.70, 1.25) 2.24 (1.71,2.92)*
Model 2 1.00 1.23 (1.02,1.67)* 0.90 (0.67,1.21) 1.36 (1.18,2.20)*
Model 3 1.00 1.16 (0.94,1.60) 0.82 (0.60,1.12) 1.23 (1.04,2.18)*

NWC, normal WC (<90 cm for men and <80 cm for women); HWC, higher WC (≥90 cm for men and ≥80 cm for women); HHcy (–): without HHcy; HHcy (+): with HHcy.

NWC/HHcy (–) group used as reference.

*

P <0.05.

Model 1: Unadjusted.

Model 2: Data adjusted for age, sex, current smoking, current drinking and activity.

Model 3: Data adjusted for age, sex, current smoking, current drinking, activity, hypolycemia therapy, lipid-lowering therapy and creatinie.

WC, waist circumference; HHcy, hyperhomocysteinamia; CVD, cardiovascular disease; HR, hazard ratio.