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. 2022 Feb 12;9(2):249. doi: 10.3390/children9020249

Figure 3.

Figure 3

Moderna vaccine general characteristics, storage properties, administration dosages and variants’ efficacy. High: the receptors key-to-enter interaction mechanisms between the viral vector and the human host cell membrane. Low: the lipid-based nanoparticle with the mRNA is able to enter through a cellular endosome into the human cell. Inside the cell, the ionizable lipidic component of the endosome membrane is able to become charged positively producing a release of the lipid-based nanoparticle and mRNA into the cytoplasm. Then the ribosomes is able to synthetize proteins and messengers from mRNA producing an increase of the antibodies’ expression and an activation of the T cells’ response.