Figure 1.

Experimental details and weight changes of the mice during the allergen sensitization and consumption procedures. (A) The mice were randomly assigned to the sham group or the BLG treatment group upon arrival (week 0) and subjected to a 5-week sensitization regimen followed by a 2-week allergen exposure period. At each weekly sensitization, the mice received an intragastric administration of either 200 µL of the vehicle containing 10 μg cholera toxin (CT) or 1 mg BLG in the vehicle. Starting at week 6, all the mice were placed on a whey-containing diet for 2 weeks. Behavioral testing was carried out one day before sacrifice in week 7. (B) The growth of the sham and BLG-sensitized mice was monitored by measuring their body weight weekly during the course of the experiment. Red open circles and blue diamonds represent the group averages ± SEM for the sham mice and the BLG mice, respectively, at each timepoint (n = 10 per group).