Table 4.
Risk factors associated with mitral and aortic valves calcification.
| Variables | Calcified Mitral Valve | Calcified Aortic Valve | ||
|---|---|---|---|---|
| ORa (95% CI) | p Value | ORa (95% CI) | p Value | |
| Age | 1.024 (0.974–1.077) | 0.345 | 1.043 (0.977–1.256) | 0.300 |
| eGFR | 0.945 (0.915–0.976) | 0.001 | 0.900 (0.780–0.998) | <0.0001 |
| TNFα | 1.193 (1.019–1.397) | 0.028 | 1.340 (1.056–1.500) | 0.024 |
| Ca | 0.566 (0.267–1.197) | 0.136 | 0.574 (0.272–1.213) | 0.146 |
| P | 2.310 (1.111–4.803) | 0.025 | 4.340 (1.004–8.745) | <0.0001 |
| CaxP | 1.022 (0.945–1.105) | 0.585 | 1.026 (0.949–1.109) | 0.522 |
| PTH | 1.003 (0.999–1.006) | 0.155 | 1.006 (1.001–1.011) | 0.024 |
| Mg | 0.489 (0.254–0.942 | 0.033 | 0.332 (0.161–0.682) | 0.014 |
| GRP | 0.450 (0.234–0.657) | <0.0001 | 0.567 (0.367–0.905) | <0.0001 |
| 1.25(OH)2 Vitamin D | 1.040 (0.974–1.110) | 0.246 | 1.040 (0.974–1.110) | 0.246 |
| FGF-23 | 1.011 (1.005–1.017) | <0.0001 | 1.210(1.000–1.400) | <0.0001 |
| α-Klotho | 0.995 (0.992–0.998) | 0.002 | 0.980 (0.880–0.990) | 0.003 |
Univariate logistic regression analysis. ORa, adjusted odds ratio; CI, confidence interval; eGFR, estimated glomerular filtration rate; TNFα, tumour necrosis factor alpha; P, phosphate; Ca, calcium; CaxP, calcium x phosphate; PTH, parathyroid hormone; Mg, magnesium; GRP, Gla-rich protein; FGF-23, fibroblast growth factor 23.