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. 2022 Feb 15;12(2):496. doi: 10.3390/diagnostics12020496

Table 5.

GRP is an independent risk factor associated with mitral and aortic valves calcification.

Variables Calcified Mitral Valve Calcified Aortic Valve
ORa (95% CI) p Value ORa (95% CI) p Value
eGFR 0.995 (0.935–1.058) 0.865 0.902 (0.905–1.042) 0.440
TNFα 1.043 (0.843–1.245) 0.188 1.105 (0.929–1.401) 0.184
P 1.078 (1.000–1.612) 0.001 1.497 (1.004 -2.378) 0.002
GRP 0.268 (0.101–0.725) 0.005 0.202 (0.109–0.401) 0.022
Mg 0.747 (0.263–0.921) 0.003 0.580 (0.173–0.948) 0.008
FGF-23 1.209 (1.099–1.619) 0.035 1.126 (1.034–1.436) 0.011
α-Klotho
PTH
1.002 (0.997–1.037 0.505 1.002 (0.995–1.009)
0.999 (0.890–1.002)
0.564
0.055

Multivariate logistic regression. ORa, adjusted odds ratio; CI, confidence interval; eGFR, estimated glomerular filtration rate; TNFα, tumour necrosis factor alpha; P, phosphate; Mg, magnesium; GRP, Gla-rich protein; FGF-23, fibroblast growth factor 23; PTH, parathyroid hormone.