Table 6.

GRP, Mg and P are cumulative risk factors for valvular calcifications.

Variables	Calcified Mitral Valve				Calcified Aortic Valve
	aPR	Robust Std. Err.	(95% CI)	p Value	aPR	Robust Std. Err.	(95% CI)	p Value
Age	1.023	0.0530	0.500–1.054	0.130	1.018	0.0175	0.987–1.050	0.263
eGFR	1.003	0.1310	0.978–1.015	0.813	0.999	0.0189	0.963–1.037	0.962
TNFα	1.035	0.0255	0.984–1.088	0.179	1.037	0.236	0.990–1.086	0.125
Ca	0.470	0.1297	0.304–1.105	0.136	0.752	0.3234	0.399–1.416	0.377
P	1.110	0.0352	1.001–2.803	0.032	1.720	0.3054	1.396–3.310	0.002
CaxP	1.011	0.0259	0.961–1.064	0.677	0.965	0.0262	0.917–1.016	0.179
Mg	0.762	0.2779	0.256–0.963	0.028	0.809	0.3712	0.391–0.974	0.006
PTH	1.000	0.0010	0.998–1.002	0.790	1.003	0.1008	0.901–1.124	0.071
GRP	0.750	0.0197	0.456–0.976	0.024	0.813	0.2430	0.113–0.937	<0.0001
1.25(OH)2 Vitamin D	1.020	0.0175	0.986–1.056	0.253	0.991	0.0126	0.967–1.016	0.489
FGF-23	1.002	0.0116	0.999–1.005	0.204	0.998	0.1021	0.994–1.003	0.258
α-Klotho	1.000	0.0015	0.996–1.002	0.818	1.000	0.0014	0.998–1.003	0.843

Robust Poisson regression model. aPR: adjusted prevalence ratios; 95% CI for aPR: 95% confidence interval for the prevalence ratios (PR); eGFR, estimated glomerular filtration rate; TNFα, tumour necrosis factor alpha; Ca, calcium; P, phosphate; CaxP, calcium x phosphate; Mg, magnesium; PTH, parathyroid hormone; GRP, Gla-rich protein; FGF-23, fibroblast growth factor 23.