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. 2022 Jan 30;29(2):698–723. doi: 10.3390/curroncol29020061

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Poorly differentiated hepatocellular carcinoma in a 69-year-old man. The axial T2-weighted image (A) shows a moderately hyperintense lesion (arrow) in liver segment VII. On plain T1-weighted image (B), the tumor (arrow) shows central hyperintensity and peripheral hypointensity, with only a slight ring enhancement in the arterial phase (C). The tumor (arrow) remains centrally hypointense in the portal venous (D) and delayed phases (E) with irregular nodular peripheral enhancement. Hematoxylin and eosin (H&E) staining showed poorly differentiated HCC; original magnification ×40 (F).