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. 2022 Feb 6;12(2):419. doi: 10.3390/diagnostics12020419

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Volcano plots illustrate differentially abundant proteins between the eutopic endometrium from control and endometriosis patients. The log10 (binomial p-value) is plotted against the log Ratio. The non-axial vertical lines denote a ± two-fold change while the non-axial horizontal line denotes p ≥ 1.3, which was our significance threshold (prior to logarithmic transformation). Proteins upregulated with a fold change ≥ 2 and p < 0.05 are depicted in red circles and those downregulated with a fold change ≥ 2 and p < 0.05 are shown in blue triangles. The proteins shown in grey were not found to differ significantly between the eutopic endometrium of controls and that of endometriosis patients; (b) Principal Component Analysis (PCA) applied to all samples based on the expression data of all identified proteins, i.e., fives controls and four endometrioses; (c) PCA applied to all samples based on the expression data of the 543 differential proteins.

(a) Volcano plots illustrate differentially abundant proteins between the eutopic endometrium from control and endometriosis patients. The log10 (binomial p-value) is plotted against the log Ratio. The non-axial vertical lines denote a ± two-fold change while the non-axial horizontal line denotes p ≥ 1.3, which was our significance threshold (prior to logarithmic transformation). Proteins upregulated with a fold change ≥ 2 and p < 0.05 are depicted in red circles and those downregulated with a fold change ≥ 2 and p < 0.05 are shown in blue triangles. The proteins shown in grey were not found to differ significantly between the eutopic endometrium of controls and that of endometriosis patients; (b) Principal Component Analysis (PCA) applied to all samples based on the expression data of all identified proteins, i.e., fives controls and four endometrioses; (c) PCA applied to all samples based on the expression data of the 543 differential proteins.