The expression levels of the top six miRNAs in patients with active tuberculosis (ATB) before, during and after treatment. The expression levels of (a) miR-199b-3p, (b) miR-199a-3p, (c) miR-6886-3p, (d) miR-6856-3p, (e) miR-16-5p, and (f) miR-374c-5p were measured in patients with ATB collected at the time of diagnosis (T0), after two months of therapy (T2), and after the completion of therapy (T6; 6–9 months after T0). The blue dotted line is representative of the mean miRNA expression level of the healthy control (HC) patients. The data are shown as mean ± standard error of the mean. * p < 0.05, ** p < 0.001, *** p < 0.0001.