Table 6.

SVM classification results between normal and different stage of glaucomatous eyes using each OCT-related feature groups (plus age, gender, and refraction).

	10-Fold Cross-Validation
Normal	254 eyes
Early stage	337 eyes
Feature Group	Sensitivity	Specificity	Accuracy	AUC
AGR	0.91	0.18	0.60	0.58
OCT + AGR	0.79	0.71	0.75	0.78
MRW + AGR	0.73	0.70	0.72	0.77
ppNFLT + AGR	0.76	0.72	0.74	0.77
RAT + AGR	0.74	0.47	0.72	0.67
NFL + AGR	0.80	0.64	0.73	0.73
GCL + AGR	0.73	0.76	0.70	0.75
IPL + AGR	0.73	0.76	0.70	0.72
RAT 8 × 8 + AGR	0.76	0.60	0.69	0.58
Normal	254 eyes
Moderate stage	73 eyes
Feature Group	Sensitivity	Specificity	Accuracy	AUC
AGR	0.04	1	0.77	0.66
OCT + AGR	0.72	0.96	0.91	0.89
MRW + AGR	0.60	0.97	0.89	0.86
ppNFLT + AGR	0.78	0.97	0.93	0.89
RAT + AGR	0.45	0.97	0.85	0.79
NFL + AGR	0.67	0.97	0.91	0.84
GCL + AGR	0.72	0.97	0.91	0.85
IPL + AGR	0.63	0.97	0.89	0.84
RAT 8 × 8 + AGR	0.63	0.95	0.88	0.75
Normal	254 eyes
Severe stage	88 eyes
Feature Group	Sensitivity	Specificity	Accuracy	AUC
AGR	0.73	0.73	0.73	0.68
OCT + AGR	0.96	0.96	0.96	0.93
MRW + AGR	0.94	0.94	0.94	0.92
ppNFLT + AGR	0.96	0.96	0.96	0.92
RAT + AGR	0.92	0.92	0.92	0.88
NFL + AGR	0.95	0.95	0.95	0.93
GCL + AGR	0.95	0.95	0.95	0.92
IPL + AGR	0.94	0.94	0.94	0.90
RAT 8 × 8 + AGR	0.68	0.68	0.73	0.70

AGR: age, gender, refraction; OCT: all optical coherence tomography parameters; MRW: minimal rim width; ppNFLT: peripapillary nerve fiber layer thickness; RAT: retinal average thickness in 1, 3, 6 mm ETDRS grid; NFL: nerve fiber layer in 1, 3, 6 mm ETDRS grid; GCL: ganglion cell layer in 1, 3, 6 mm ETDRS grid; IPL: inner plexiform layer in 1, 3, 6 mm ETDRS grid; RAT: retinal average thickness in 8 × 8 grid; AUC: area under the receiver operating characteristic curve.