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. 2022 Jan 28;24(2):203. doi: 10.3390/e24020203
Algorithm 2 A fast operational scheme of Algorithm 1.
  • 1.

    Step 2.1 of Algorithm 1 is performed by running the linear mixed model with our initial fixed γ from Step 1.2 of Algorithm 1 to obtained updated values of λ1, β, and α.

  • 2.

    Step 2.2 is performed with solving the group regularity problem (8) through the Gauss–Newton algorithm using cross-validation-based tuning (e.g., R package oem).

  • 3.

    Rerun Step 2.1 using the updated γ from Step 2.2 to obtain the estimates for β and α.