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. 2022 Feb 14;12(2):495. doi: 10.3390/diagnostics12020495

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Plots of the structural similarity (SSIM) vs. reference vs. without pre-reconstruction processing, reference vs. with multiscale bilateral filtering (MSBF) pre-reconstruction processing, reference vs. pix2pix pre-reconstruction processing from the in-focus plane for low dose with variant phantom thickness. (a) In-focus plane for evaluation of 0.19- and 0.23-mm microcalcifications (MCs); (b) in-focus plane for evaluation of 0.29-mm MCs and 3.9-mm masses; (c) in-focus plane for evaluation of 4.7-mm mass. h: approximately 50% reduction of automatic exposure control reference dose (AECrd); q: approximately 75% reduction of AECrd. (Tukey–Kramer test; p < 0.05 indicates a significant difference, *: significant).