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Body weight and survival rate of the rats. HF was induced by ligation of left coronary artery, and rats were treated with vehicle (saline) or different doses of ASI (0.1, 0.3 and 1 mg/kg/day) by oral gavage for 6 weeks. A. Body weight. B. Kaplan–Meier survival curve. Data are presented as Mean ± SD. N = 10–15. ##p < 0.01, ###p < 0.001 vs. sham group. ***p < 0.001 vs. model group.
