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. 2019 Mar 24;57(1):48–54. doi: 10.1080/13880209.2019.1569697

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — JAK-STAT3 pathway. The protein expression and phosphorylation of JAK and STAT3 in the ventricular tissue was determined by Western blot. A. Representative photographs of Western blot. B. Statistical analysis of Western blot. C. Activity of VEGF promoter. The nuclear extract was isolated from the ventricular tissue and used to perform chromatin immunoprecipitation with an STAT3 antibody. The change of downstream promoter was analyzed by real-time PCR. Data are presented as Mean ± SD. N = 6. ***p < 0.001 vs. model group.