Table 2.
Linear regression results for whole blood metals (log-transformed) with each cognitive function score, adjusted for sociodemographic, behavior, and clinical characteristics 1.
| CERAD Immediate Recall | CERAD Delayed Recall | Digit Symbol Substitution | ||||
|---|---|---|---|---|---|---|
| β (95% CI) | p Value | β (95% CI) | p Value | β (95% CI) | p Value | |
| Cadmium, µg/L (n = 2031) | −0.54 (−0.90, −0.17) | <0.01 | −0.19 (−0.37, −0.01) | 0.04 | −2.29 (−3.41, −1.16) | <0.01 |
| Lead, µg/L (n = 2146) | −0.58 (−0.91, −0.24) | <0.01 | −0.19 (−0.35, −0.02) | 0.03 | −1.08 (−2.12, −0.05) | 0.04 |
| Manganese, µg/L (n = 2146) | −0.16 (−0.73, 0.42) | 0.59 | 0.24 (−0.05, 0.52) | 0.10 | 0.63 (−1.14, 2.39) | 0.48 |
| Selenium, µg/L (n = 2146) | 2.68 (1.06, 4.30) | <0.01 | 0.87 (0.06, 1.67) | 0.04 | 8.38 (3.40, 13.36) | <0.01 |
| Total mercury, µg/L (n = 2036) | 0.20 (−0.03, 0.42) | 0.09 | 0.06 (−0.05, 0.17) | 0.29 | 0.56 (−0.12,1.25) | 0.11 |
| Inorganic mercury, µg/L (n = 648) | 0.58 (−0.31, 1.47) | 0.20 | −0.33 (−0.76, 0.09) | 0.12 | −2.35 (−5.07, 0.36) | 0.09 |
| Methylmercury, µg/L (n = 1939) | 0.11 (−0.09, 0.31) | 0.28 | 0.07 (−0.03, 0.17) | 0.17 | 0.21 (−0.40, 0.83) | 0.50 |
1 Models adjusted for age, sex, race/ethnicity, education level, depression, diabetes, cigarette smoking, and alcohol consumption.