Table 4.
Comparison of blood parameters between participants with different BMI.
| Variables | Lean/Normal Weight MAFLD (%) | Overweight MAFLD (%) | Obese MAFLD (%) | Non-MAFLD (%) | p |
|---|---|---|---|---|---|
| N | 724 (0.98) | 2012 (2.74) | 21,096 (28.68) | 49,734 (67.60) | |
| Age group | |||||
| 25–29 | 115 (15.88) | 205 (10.19) | 2029 (9.62) | 7467 (15.01) | <0.001 |
| 30–39 | 148 (20.44) | 404 (20.08) | 4306 (20.41) | 11,731 (23.59) | |
| 40–49 | 111 (15.33) | 372 (18.49) | 3930 (18.63) | 9132 (18.36) | |
| 50–59 | 148 (20.44) | 483 (24.01) | 5372 (25.46) | 10,068 (20.24) | |
| ≥60 | 202 (27.90) | 548 (27.24) | 5459 (25.88) | 11,336 (22.79) | |
| Gender | |||||
| Male | 272 (37.57) | 1019 (50.65) | 11,161 (52.91) | 21,388 (43.00) | <0.001 |
| Female | 452 (62.43) | 993 (49.35) | 9935 (47.09) | 28,346 (56.99) | |
| Hypertension (%) | |||||
| No | 515 (71.13) | 1352 (67.20) | 11,570 (54.85) | 36,358 (73.10) | <0.001 |
| Yes | 209 (28.87) | 660 (32.80) | 9526 (45.15) | 13,376 (26.90) | |
| Diabetes DM (%) | |||||
| No | 635 (87.71) | 1649 (81.96) | 16,844 (79.84) | 45,387 (91.26) | <0.001 |
| Yes | 89 (12.29) | 363 (18.04) | 4252 (20.16) | 4347 (8.74) | |
| Waist circumference (cm) | 80.17 ± 7.53 a | 85.36 ± 6.60 ab | 95.604 ± 8.88 abc | 82.17 ± 9.73 abc | <0.001 |
| Hip circumference (cm) | 93.90 ± 5.41 a | 96.94 ± 5.38 ab | 104.78 ± 7.17 abc | 95.96 ± 6.97 abc | <0.001 |
| ALT (IU/L) | 23.78 ± 44.53 a | 25.43 ± 17.39 ab | 30.22 ± 25.67 abc | 18.87 ± 14.80 abc | <0.001 |
| AST (IU/L) | 23.96 ± 30.30 a | 23.33 ± 15.79 b | 24.72 ± 15.63 bc | 20.94 ± 10.86 abc | <0.001 |
| TP (g/L) | 78.30 ± 4.93 a | 78.41 ± 4.89 bc | 78.15 ± 4.91 bc | 77.53 ± 4.88 abc | <0.001 |
| ALB (g/L) | 48.32 ± 3.50 a | 48.76 ± 3.467 ab | 48.60 ± 3.25 abc | 48.75 ± 3.11 ac | <0.001 |
| TBIL (umol/L) | 12.25 ± 5.42 | 12.56 ± 5.33 b | 12.17 ± 5.20 bc | 12.43 ± 5.14 c | <0.001 |
| DBIL (umol/L) | 3.47 ± 2.14 a | 3.56 ± 1.84 b | 3.53 ± 1.81 c | 3.66 ± 1.77 abc | <0.001 |
| IBIL (umol/L) | 8.78 ± 3.83 | 9.01 ± 3.83 b | 8.64 ± 3.82 bc | 8.77 ± 3.75 bc | <0.001 |
| ALP (IU/L) | 86.94 ± 31.32 a | 89.57 ± 25.05 ab | 91.45 ± 26.50 abc | 83.65 ± 26.20 abc | <0.001 |
| GGT (IU/L) | 38.89 ± 86.56 a | 37.60 ± 41.69 b | 41.77 ± 39.99 abc | 26.95 ± 33.73 abc | <0.001 |
| TBA (umol/L) | 4.29 ± 5.55 a | 4.03 ± 4.94 b | 4.08 ± 4.58 c | 3.70 ± 4.10 abc | <0.001 |
| CHE (IU/L) | 8341.40 ± 1608.05 a | 8814.04 ± 1415.35 ab | 9064.56 ± 1465.08 abc | 7993.57 ± 1474.81 abc | <0.001 |
| PA (g/L) | 0.29 ± 0.06 a | 0.30 ± 0.05 ab | 0.30 ± 0.05 abc | 0.28 ± 0.05 abc | <0.001 |
| TG (umol/L) | 1.79 ± 1.75 a | 2.06 ± 1.98 ab | 2.29 ± 2.26 abc | 1.37 ± 1.26 abc | <0.001 |
| FPG (mmol/L)) | 6.04 ± 1.97 a | 6.24 ± 2.01 ab | 6.43 ± 2.13 abc | 5.75 ± 1.60 abc | <0.001 |
| CHOL (mmo/L) | 5.06 ± 1.08 a | 5.20 ± 1.03 ab | 5.23 ± 1.06 ac | 4.99 ± 0.99 bc | <0.001 |
| HDL-C (mmo/L) | 1.41 ± 0.37 a | 1.31 ± 0.31 ab | 1.25 ± 0.29 abc | 1.43 ± 0.34 bc | <0.001 |
| LDL-C (mmo/L) | 2.92 ± 0.86 a | 3.10 ± 0.84 ab | 3.15 ± 0.85 c | 2.87 ± 0.82 bc | <0.001 |
| HbA1c (%) | 5.59 ± 1.14 a | 5.72 ± 1.18 ab | 5.83 ± 1.13 abc | 5.44 ± 0.88 abc | <0.001 |
| RBC× (1012/L) | 4.65 ± 0.46 a | 4.78 ± 0.46 ab | 4.83 ± 0.46 abc | 4.66 ± 0.45 bc | <0.001 |
| HGB (g/L) | 132.74 ± 15.31 a | 137.34 ± 14.94 ab | 139.50 ± 14.84 abc | 134.34 ± 15.25 abc | <0.001 |
| HCT (%) | 0.39 ± 0.04 a | 0.404 ± 0.035 ab | 0.41 ± 0.04 abc | 0.39 ± 0.04 abc | <0.001 |
| MCV (fl) | 84.49 ± 4.92 | 84.36 ± 4.58 b | 84.49 ± 4.21 c | 84.82 ± 4.73 bc | <0.001 |
| MCH (pg) | 28.60 ± 2.25 a | 28.81 ± 2.16 | 28.93 ± 4.80 a | 28.90 ± 2.78 a | 0.043 |
| MCHC (g/L) | 338.14 ± 13.08 a | 341.20 ± 12.97 a | 342.14 ± 56.89 ac | 340.48 ± 22.57 c | <0.001 |
| RDW (%) | 0.11 ± 0.02 | 0.11 ± 0.01 b | 0.11 ± 0.01 bc | 0.11 ± 0.01 bc | 0.001 |
| PLT (×109/L) | 199.56 ± 56.19 a | 210.80 ± 55.96 ab | 221.50 ± 58.65 abc | 217.28 ± 53.59 abc | <0.001 |
| PDW (%) | 0.20 ± 0.01 a | 0.20 ± 0.01 | 0.20 ± 0.01 ac | 0.20 ± 0.01 c | 0.002 |
| MPV (fl) | 6.32 ± 1.07 a | 6.39 ± 1.12 | 6.40 ± 1.11 | 6.41 ± 1.13 a | 0.21 |
| PCT (%) | 0.12 ± 0.03 a | 0.13 ± 0.03 ab | 0.14 ± 0.07 abc | 0.14 ± 0.04 abc | <0.01 |
| WBC (×109/L) | 6.20 ± 1.74 a | 6.44 ± 1.63 ab | 6.80 ± 1.70 abc | 6.15 ± 1.60 bc | <0.001 |
| LYM (×109/L) | 2.16 ± 0.77 a | 2.17 ± 0.61 b | 2.31 ± 0.68 abc | 2.08 ± 0.64 abc | <0.001 |
| MONO (×109/L) | 0.38 ± 0.15 a | 0.40 ± 0.15 ab | 0.42 ± 0.16 abc | 0.39 ± 0.16 bc | <0.001 |
| NEU (×109/L) | 3.48 ± 1.33 a | 3.67 ± 1.26 ab | 3.85 ± 1.27 abc | 3.50 ± 1.23 bc | <0.001 |
| EOS (×109/L) | 0.13 ± 0.12 a | 0.15 ± 0.15 ab | 0.16 ± 0.16 abc | 0.14 ± 0.14 bc | <0.001 |
| BASO (×109/L) | 0.05 ± 0.04 a | 0.06 ± 0.04 b | 0.06 ± 0.07 abc | 0.06 ± 0.04 c | <0.001 |
| Alcohol consumption (g) | 6.53 ± 34.28 | 7.82 ± 25.20 b | 8.14 ± 24.40 c | 5.93 ± 20.69 bc | <0.001 |
| LSM (Kpa) | 6.80 ± 5.27 a | 6.74 ± 3.54 b | 7.50 ± 3.03 abc | 6.10 ± 2.55 abc | <0.001 |
| UAP (dB/m) | 263.46 ± 18.78 a | 265.67 ± 19.14 ab | 276.32 ± 25.90 abc | 208.61 ± 20.81 abc | <0.001 |
The same superscript letters in two groups represent p value < 0.05 when the two groups are compared. a Compared with lean/normal weight MAFLD groups, p value < 0.05; b Compared with overweight MAFLD groups, p value < 0.05; c Compared with obese MAFLD groups, p value < 0.05.