Merged network of upregulated genes and downregulated genes. This network comprises 2091 nodes and 75,957 edges. Green colors nodes and red colors nodes indicates our key genes (downregulated and upregulated, respectively), and blue nodes are their interacting partners (other genes). Nodes are the gene entity and edges are the interactions/connections. This merged network is prepared using the Network Analyzer function in Cytoscape. The genes have a common connection in both networks and merge into one network: both networks, upregulated and downregulated, have 1306 and 1348 nodes, respectively; after merging, the total genes should be 2698, but in the merged network, this becomes 2091, because some of the genes are the same in both networks (i.e., we removed duplicate genes).