Table 5.

Summary of intervention effects.

Drug Comparisons		Results
		Persistent High BP	Maternal Hypotension	Other Side Effects
Nifedipine	Labetalol	Nifedipine had a lower risk (RR 0.71, p = 0.03; five studies)	No significant difference (RR 2.06, p = 0.49; seven studies)	No significant difference (participant experience) (RR 0.75, p = 0.28; two studies) Nifedipine: at risk of having more side effects (RR 1.57, p = 0.02; six studies)
Nicardipine	Labetalol	No significant difference (RR 0.82, p = 0.59; one study)	No incident (one study)	No significant difference (total side effects) (RR 1.07, p = 0.70; one study)
Nifedipine	Hydralazine	Nifedipine had a significantly lower risk (RR 0.40, p = 0.002; two studies)	No incident (two studies)	No significant difference (participant experience) (RR 1.03, p = 0.94; one study) Nifedipine: more at risk of headache (RR 3.69, p = 0.02; two studies)
Nifedipine	Prazosine	No significant difference (RR 0.32, p = 0.32; one study)	Not reported	Not reported
Ketanserine	Dyhidralazine	Dihydralazine had a lower risk (RR 5.26, p = 0.0007; two studies)	Dihydralazine more at risk (RR 0.42, p = 0.01; two studies)	Dihydralazine: at risk of having more side effects (RR 0.38, p = 0.0002; two studies)
Urapidil	Dyhidralazine	Not reported	Not reported	No incidence (one study)
Hydralazine	Labetalol	No significant difference (RR 1.00, p = 1.00; one study)	No significant difference (RR 5.00, p = 0.30; one study)	No significant difference (participant experience) (RR 1.06, p = 0.86; one study) Hydralazine: more at risk of palpitasion (RR 5.00, p = 0.03; one study)
Hydralazine	Diazoxide	No significant difference (RR 1.06, p = 0.85; one study)	Not reported	Not reported
Methyldopa	Nifedipine	Methyldopa had a lower risk (RR 1.43, p = 0.03; one study)	No significant difference (RR 0.20, p = 0.30; one study)	Nifedipine: at risk of having more side effects (RR 0.56, p = 0.0001; one study)
Methyldopa	Labetalol	No significant difference (RR 1.04, p = 0.8; one study)	No incident (one study)	No significant difference (total side effects) (RR 1.20, p = 0.32; one study)

Abbreviations: BP, blood pressure; RR, risk ratio. Calcium Channel Blocker versus Labetalol.