Figure 9.

Regulatory role of Baicalin on the STAT5-ID2 signal pathway in RSA mice. (a, b) The mRNA and protein expressions of STAT5, E2-2, and ID2 were analyzed in maternal-fetal interface mononuclear cells of NP mice and RSA mice treated with NS control, low-dose baicalin (25 mg/kg/day), middle-dose baicalin (50 mg/kg/day), and high-dose baicalin (100 mg/kg/day). Data were analyzed by one-way ANOVA followed by the Tukey post hoc test. Mean ± SD are shown, n = 3 − 5. ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗∗p < 0.0001, compared with NP; ^#p < 0.05; ^##p < 0.01; ^####p < 0.0001, compared with NS control. NP: normal pregnancy; NS: normal saline; RSA: recurrent spontaneous abortion.