Table 4.
Bivariable and multivariate Cox regression for predictors of mortality of undernourished HIV-positive children among selected health facility of Northwest Ethiopia 2009-2020.
| Variables | Categories | Survival status | CHR (95% CI) | AHR (95% CI) | |
|---|---|---|---|---|---|
| Died | Censored | ||||
| Sex | Male | 35 | 302 | 1 | 1 |
| Female | 56 | 328 | 1.3 (0.88, 2.07) | 1.7 (0.70, 1.70) | |
| Age | ≤60 months | 29 | 49 | 2.8 (1.70, 4.60) | 1.7 (0.79, 3.20) |
| 61–120 months | 23 | 231 | 1.2 (0.79, 2.11) | 2.5 (0.93, 4.50) | |
| ≥121 months | 38 | 351 | 1 | 1 | |
| Residence | Urban | 61 | 449 | 1.16 (0.73, 1.87) | 1.12 (0.7, 1.85) |
| Rural | 29 | 182 | 1 | 1 | |
| CD4 count | Below threshold | 70 | 238 | 3.12 (1.90, 7.20) | 1.6 (1.19, 7.85)∗ |
| Above threshold | 20 | 393 | 1 | 1 | |
| WHO stage | Stages I and II | 8 | 435 | 1 | 1 |
| Stages III and IV | 82 | 196 | 10.9 (5.20, 22.70) | 4.5 (2.80, 8.40)∗ | |
| Adherence | Optimal adherence | 21 | 489 | 1 | 1 |
| Suboptimal adherence | 69 | 142 | 6.3 (3.80, 10.30) | 1.8 (0.60, 3.60) | |
| Dietary counseling | Yes | 44 | 421 | 1 | 1 |
| No | 46 | 210 | 1.8 (1.50, 2.50) | 1.9 (0.50, 1.50) | |
| Disclosure status | Yes | 54 | 104 | 3.3 (2.30, 5.10) | 1.7 (0.59, 2.8) |
| No | 36 | 527 | 1 | 1 | |
| Duration of follow-up | ≤36 months | 6 | 217 | 1 | 1 |
| 37–72 months | 19 | 276 | 2.1 (0.90, 5.10) | 2.1 (0.70, 5.70) | |
| >72 months | 65 | 138 | 7.1 (3.10, 16.30) | 2.6 (0.80, 3.60) | |
| Wasting | Normal | 70 | 461 | 1 | 1 |
| Moderate (WHZ or BAZ < −2) | 18 | 101 | 9.6 (1.28, 12.6) | 0.8 (0.18, 4.30) | |
| Severe (WHZ or BAZ < −3) | 2 | 69 | 7.8 (1.80, 16.30) | 1.07 (0.50, 1.90) | |
| Underweight | Normal | 34 | 457 | 1 | 1 |
| Moderate (WAZ < −2) | 18 | 126 | 1.6 (0.91, 2.91) | 0.6 (0.30, 1.17) | |
| Severe (WAZ < −3) | 38 | 48 | 2.9 (1.80, 4.82) | 1.2 (0.60, 2.1) | |
| Stunting | Normal | 18 | 410 | 1 | 1 |
| Moderate (HAZ < −2) | 29 | 125 | 5.6 (2.50, 8.40) | 1.6 (0.80, 3.20) | |
| Severe (HAZ < −3) | 43 | 96 | 4.6 (3.20, 9.90) | 2.9 (1.80, 6.40)∗ | |
| MUAC | ≤11.5 cm | 56 | 214 | 4.5 (2.10, 6.10) | 1.5 (0.60, 4.20) |
| >11.5 cm | 34 | 417 | 1 | 1 | |
| CPT | Yes | 17 | 402 | 1 | 1 |
| No | 73 | 229 | 2.5 (1.60, 7.60) | 1.2 (0.43, 4.50) | |
| SAM admission history | Yes | 37 | 91 | 2.8 (1.80, 4.30) | 1.7 (0.60, 2.90) |
| No | 53 | 540 | 1 | 1 | |
CHR = crude hazard ratio; AHR = adjusted hazard ratio; CI = confidence interval; 1 = reference category. ∗Significant predictors variables on final the multivariable models at P < 0.05.