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. 2022 Feb 22;119(8):e2110293119. doi: 10.1073/pnas.2110293119

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Fig. 3. — Mtb nrps modulates host free-zinc dynamics. (A) Free-zinc labeling using FZ3-AM dye for uninfected, mCherry-labeled WT, Δnrps, and Δnrps:nrps Mtb strains infected murine macrophages 2 h postinfection. (B) FZ3-AM signal quantitation from 75 cells for each condition. Unlike WT and Δnrps:nrps-infected macrophages, Δnrps-infected macrophages do not show elevated free-zinc levels as compared to uninfected macrophage. Data represent mean ± SEM (n = 3 biological replicates) with P values indicated for each data point.