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These diagrams depict the two transmission events examined. (A) An infected nymph (+) feeding on an uninfected white-footed mouse (−). Prior to, during, and after feeding, the spirochetes in the ticks' midguts were examined for expression of OspA and OspC. (B) An uninfected nymph (−) feeding on an infected white-footed mouse (+). The spirochetes that were acquired during tick feeding and that were in the ticks' midguts were examined for expression of OspA and OspC.
