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. 2021 Jun 22;26(12):7760–7783. doi: 10.1038/s41380-021-01189-9

Table 1.

Top differentially expressed proteins (relative to Ctrls) detected via TMT-LC/MS.

Short protein name Long protein name Uniprot accession ANOVA p value
NDUFAF2 NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex Assembly Factor 2 Q8N183 0.000481025
TMEM50B Transmembrane Protein 50B P56557 0.000548505
IMPA1 Inositol Monophosphatase 1 P29218 0.001902383
ARMCX1 Armadillo Repeat-Containing X-Linked Protein 1 Q9P291 0.002196252
GBF1 Golgi-Specific Brefeldin A-Resistance Guanine Nucleotide Exchange Factor 1 Q92538-3 0.002520107
HDHD5 Haloacid Dehalogenase-Like Hydrolase Domain-Containing 5 Q9BXW7-2 0.00307041
GTPBP4 Nucleolar GTP-Binding Protein 1 Q9BZE4 0.00324609
ARF4 ADP-Ribosylation Factor 4 P18085 0.003766362
GRPEL1 GrpE Protein Homolog 1, Mitochondrial Q9HAV7 0.004413199
ACAT2 Acetyl-CoA Acetyltransferase, Cytosolic Q9BWD1 0.004730022
MANF Mesencephalic Astrocyte-Derived Neurotrophic Factor P55145 0.005179981
DOCK4 Dedicator of Cytokinesis Protein 4 Q8N1I0–2 0.00538423
TXNRD1 Thioredoxin-Disulfide Reductase E9PIR7 0.005572821
DIABLO Diablo Homolog, Mitochondrial Q9NR28-2 0.00627476
HSPA13 Heat Shock 70 kDa Protein 13 P48723 0.00627476
TFCP2 Alpha-Globin Transcription Factor CP2 Q12800-2 0.00639284
DYNLT1 Dynein Light Chain Tctex-Type 1 P63172 0.00671083
HDGF Hepatoma-Derived Growth Factor P51858 0.007032222
PSMB7 Proteasome Subunit Beta Type-7 Q99436 0.007289525
UNK RING Finger Protein Unkempt Homolog Q9C0B0 0.008045913
HYOU1 Hypoxia Up-Regulated Protein 1 Q9Y4L1 0.008687815
SEC62 Translocation Protein SEC62 Q99442 0.010325685
APLP2 Amyloid-Like Protein 2 Q06481-4 0.013408141
USP7 Ubiquitin Carboxyl-Terminal Hydrolase 7 Q93009-3 0.015504379
KATNAL1 Katanin p60 ATPase-Containing Subunit A-Like 1 Q9BW62 0.015622147
HSPA5 Endoplasmic Reticulum Chaperone BiP P11021 0.015742232
DYNC1LI1 Cytoplasmic Dynein 1 Light Intermediate Chain 1 Q9Y6G9 0.016475164
ABCF1 ATP-Binding Cassette Sub-Family F Member 1 Q8NE71-2 0.016611257
SHMT2 Serine Hydroxymethyltransferase, Mitochondrial P34897-3 0.018482781
DHTKD1 Probable 2-Oxoglutarate Dehydrogenase E1 Component DHKTD1, Mitochonondrial Q96HY7 0.018748869
SLC7A1 High Affinity Cationic Amino Acid Transporter 1 P30825 0.021172737
PIK3C2B Phosphatidylinositol 4-Phosphate 3-Kinase C2 Domain-Containing Subunit Beta O00750 0.021899148
SORBS1 Sorbin and SH3 Domain-Containing Protein 1 Q9BX66-4 0.024998617
HSPA9 Stress-70 Protein, Mitochondrial P38646 0.027136132
CCDC47 Coiled-Coil domain-Containing Protein 47 Q96A33 0.028644274
ALG2 Alpha-1,3/1,6-Mannosyltransferase ALG2 Q9H553 0.030668953
APP Amyloid-Beta Precursor Protein P05067-11 0.031024857
SUPT6H Transcription Elongation Factor SPT6 Q7KZ85 0.033263913
RRP12 RRP12-Like Protein Q5JTH9-2 0.033924326
MLF2 Myeloid Leukemia Factor 2 Q15773 0.043882525
RPS13 40 s Ribosomal Protein S13 P62277 0.047438594