Table 4.
Cost-effectiveness results
| Number of patients | Mean adjusted costs*(95% CI) | Mean adjusted QALYs*(95% CI) | Mean incremental costs (95% CI) | Incremental QALYs (95% CI) | Mean incremental net monetary benefit at £20 000 per QALY (95% CI) | |
|---|---|---|---|---|---|---|
| NHS and personal social services perspective | ||||||
| Intervention | 242 | £1961·84 (1531·05 to 2392·63) | 0·52 (0·50 to 0·54) | .. | .. | .. |
| Usual care | 121 | £2686·28 (2034·86 to 3337·69) | 0·50 (0·47 to 0·52) | .. | .. | .. |
| Intervention vs usual care | .. | .. | .. | −£724·43 (−1500·27 to 51·39) | 0·027 (−0·008 to 0·06) | £1256 (164 to 2348) |
| Patient perspective | ||||||
| Intervention | 242 | £375·52 (155·32 to 595·71) | 0·52 (0·50 to 0·54) | .. | .. | .. |
| Usual care | 121 | £682·90 (307·25 to 1058·55) | 0·50 (0·47 to 0·53) | .. | .. | .. |
| Intervention vs usual care | .. | .. | .. | −£307·38 (−745·70 to 130·94) | 0·027 (−0·008 to 0·06) | £865 (−91 to 1822) |
| NHS, personal social services, and patient perspective | ||||||
| Intervention | 242 | £2337·36 (1850·53 to 2824·19) | 0·52 (0·50 to 0·54) | .. | .. | .. |
| Usual care | 121 | £3369·17 (2603·26 to 4135·09) | 0·50 (0·47 to 0·52) | .. | .. | .. |
| Intervention vs usual care | .. | .. | .. | −£1031·81 (−1936·58 to −127·05) | 0·027 (−0·008 to 0·06) | £1564 (369 to 2758) |
QALY=quality-adjusted life-year. NHS=UK National Health Service. BPI=Brief Pain Inventory.
*
All variables are adjusted for hospital site and baseline BPI subscores; additionally, QALYs were adjusted for baseline utility.